Protein redesign by learning from data
نویسندگان
چکیده
منابع مشابه
Protein redesign by learning from data.
Protein redesign methods aim to improve a desired property by carefully selecting mutations in relevant regions guided by protein structure. However, often protein structural requirements underlying biological characteristics are not well understood. Here, we introduce a methodology that learns relevant mutations from a set of proteins that have the desired property and demonstrate it by succes...
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ژورنال
عنوان ژورنال: Protein Engineering, Design and Selection
سال: 2014
ISSN: 1741-0134,1741-0126
DOI: 10.1093/protein/gzu031